The role of prostaglandins in the regulation of cell proliferationWICKREMASINGHE, R. G.Prostaglandins, leukotrienes and essential fatty acids. 1988, Vol 31, Num 4, pp 171-179, issn 0952-3278Article

Chronic myeloid leukaemia and the Philadelphia translocation: do the c-sis oncogene and platelet-derived growth factor provide the link? = Leucémie myéloïde chronique et la translocation Philadelphie: l'oncogène c-sis et le facteur de croissance dérivé des plaquettes fournissent-ils le lien?FRANCIS, G. E; MICHALEVICZ, R; WICKREMASINGHE, R. G et al.Leukemia research. 1983, Vol 7, Num 6, pp 817-820, issn 0145-2126Article

Retinoic acid-induced granulocytic differentiation of HL60 human promyelocyttic leukemia cells is preceded by downregulation of autonomous generation of inositol lipid-derived second messengersPORFIRI, E; HOFFBRAND, A. V; WICKREMASINGHE, R. G et al.Blood. 1991, Vol 78, Num 4, pp 1069-1077, issn 0006-4971Article

Editorial: phospholipases C and A₂ in malignant cell proliferationWICKREMASINGHE, R. G; JEREMY, J. Y.Prostaglandins, leukotrienes and essential fatty acids. 1989, Vol 36, Num 4, pp 199-201, issn 0952-3278Article

Inhibitors of arachidonic acid lipoxygenase impair the stimulation of inositol phospholipid hydrolysis by the T lymphocyte mitogen phytohaemagglutininMIRE-SLUIS, A. R; COX, C. A; HOFFBRAND, A. V et al.FEBS letters. 1989, Vol 258, Num 1, pp 84-88, issn 0014-5793Article

The binding of ligands to the 55 kDa component of the interleukin-2 receptor triggers increased turnover of phosphate bound to an 85 kDa protein: evidence for the role of cyclic AMPMIRE-SLUIS, A. R; HOFFBRAND, A. V; WICKREMASINGHE, R. G et al.FEBS letters. 1989, Vol 243, Num 2, pp 280-284, issn 0014-5793, 5 p.Article

Regulation of transcription factors NFκB and AP-1 following tumour necrosis factor-α treatment of cells from chronic B cell leukaemia patientsJABBAR, S. A. B; HOFFBRAND, A. V; WICKREMASINGHE, R. G et al.British journal of haematology. 1994, Vol 86, Num 3, pp 496-504, issn 0007-1048Article

Two major tyrosine protein kinases of resting human T lymphocytes are down-regulated following mitotic stimulationHALL, B. S; HOFFBRAND, A. V; WICKREMASINGHE, R. G et al.FEBS letters. 1987, Vol 223, Num 1, pp 6-10, issn 0014-5793Article

Deletion of chromosome 13 (band q14) but not trisomy 12 is a clonal event in B-chronic lymphocytic leukaemia (CLL)JABBAR, S. A. B; KANAGASABAI GANESHAGURU; WICKREMASINGHE, R. G et al.British journal of haematology. 1995, Vol 90, Num 2, pp 476-478, issn 0007-1048Article

Redox reagents and staurosporine inhibit stimulation of the transcription regulator NF-κβ following tumour necrosis factor treatment of chronic B-leukaemia cellsJABBAR, S. A. B; HOFFBRAND, A. V; WICKREMASINGHE, R. G et al.Leukemia research. 1994, Vol 18, Num 7, pp 523-530, issn 0145-2126Article

Human T lymphocytes stimulated by phytohaemagglutinin undergo a single round of cell division without a requirement for interleukin-2 or accessory cellsMIRE-SLUIS, A. R; WICKREMASINGHE, R. G; HOFFBRAND, A. V et al.Immunology (Oxford). 1987, Vol 60, Num 1, pp 7-12, issn 0019-2805Article

p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategiesWICKREMASINGHE, R. G; PRENTICE, A. G; STEELE, A. J et al.Leukemia. 2011, Vol 25, Num 9, pp 1400-1407, issn 0887-6924, 8 p.Article

Do leukotrienes play a role in the regulation of proliferation of normal and leukemic hemopoietic cells ?WICKREMASINGHE, R. G; KHAN, M. A; HOFFBRAND, A. V et al.Prostaglandins, leukotrienes and essential fatty acids. 1993, Vol 48, Num 2, pp 123-126, issn 0952-3278Article

Phytohemagglutinin treatment of T lymphocytes stimulates rapid increases in activity of both particulate and cytosolic protein kinase CMIRE, A. M; WICKREMASINGHE, R. G; HOFFBRAND, A. V et al.Biochemical and biophysical research communications (Print). 1986, Vol 137, Num 1, pp 128-134, issn 0006-291XArticle

Antioxidants enhance the susceptibility of colon carcinoma cells to 5-fluorouracil by augmenting the induction of the bax proteinADEYEMO, Dayo; IMTIAZ, F; TOFFA, S et al.Cancer letters. 2001, Vol 164, Num 1, pp 77-84, issn 0304-3835Article

Herbimycin A accelerates the induction of apoptosis following etoposide treatment or γ-irradiation of bcr/abl-positive leukaemia cellsRIORDAN, F. A; BRAVERY, C. A; MENGUBAS, K et al.Oncogene (Basingstoke). 1998, Vol 16, Num 12, pp 1533-1542, issn 0950-9232Article

Impaired degradation of Ca²⁺ -regulating second messengers in myeloid leukemia cells. Implications for the regulation of leukemia cell proliferationNYE, K. E; RILEY, G. A; POULTER, L. W et al.Leukemia. 1992, Vol 6, Num 8, pp 801-805, issn 0887-6924Article

CCK2 gastrin receptor as a potential target for therapy in leukaemia cell linesSTUBBS, M; KHAN, K; WICKREMASINGHE, R. G et al.Oncology reports. 2005, Vol 14, Num 4, pp 1055-1058, issn 1021-335X, 4 p.Article

Activation-associated necrosis in human immunodeficiency virus infectionBORTHWICK, N. J; WICKREMASINGHE, R. G; LEWIN, J et al.The Journal of infectious diseases. 1999, Vol 179, Num 2, pp 352-360, issn 0022-1899Article

Antioxidants impair the coupling of cell-surface ligand receptors to the inositol lipid signalling pathway in human T lymphocytes but not in Jurkat T lymphoblastic leukemia cells. Evidence that leukotrienes are not involved in the coupling mechanismAYYUB KHAN, M; JEREMY, J. Y; HALLINAN, T et al.Biochimica et biophysica acta. Molecular cell research. 1993, Vol 1178, Num 2, pp 215-220, issn 0167-4889Article

Binding of G-CSF, GM-CSF, tumor necrosis factor-α, and γ-interferon to cell surface receptors on human myeloid leukemia cells triggers rapid tyrosine and serine phosphorylation of a 75-Kd proteinEVANS, J. P. M; MIRE-SLUIS, A; HOFFBRAND, A. V et al.Blood. 1990, Vol 75, Num 1, pp 88-95, issn 0006-4971Article

The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitroSTEELE, A. J; JONES, D. T; HOFFBRAND, A. V et al.Leukemia. 2006, Vol 20, Num 6, pp 1073-1079, issn 0887-6924, 7 p.Article

Phytohemagglutinin-induced changes in tyrosine protein kinase and its endogenous substrates in human lymphocytesPIGA, A; WICKREMASINGHE, R. G; TAHERI, M. R et al.Experimental cell research. 1985, Vol 159, Num 1, pp 103-112, issn 0014-4827Article